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J Natl Med Assoc ; 113(2): 212-217, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-894055

ABSTRACT

OBJECTIVE: To investigate and evaluate the clinical features of patients infected with the 2019 novel coronavirus (COVID-19) outside of Wuhan. METHODS: 105 patients admitted to our hospital with clinical- and laboratory-confirmed COVID-19 infection were studied. Data were collected from January 17, 2020 to March 5, 2020. RESULTS: 105 patients (57 male and 48 female) were confirmed to have COVID-19 infection. Among the 105 patients, 55 (52%) had made short trips to Wuhan during the two weeks before the onset of illness, and these were the first-generation confirmed cases. An exact date of close contact with someone in Wenzhou with confirmed or suspected COVID-19 infection from Wuhan (the second-generation confirmed cases) could be provided by 38 (36%) patients. Of the remaining patients, six (6%; the third-generation confirmed cases) were familial clusters of the second-generation confirmed cases, three (3%) had no definite epidemiological features, and 16 (15%) were from the same location as for the case report. CONCLUSION: Due to the infectiousness of COVID-19, patients with infections should be diagnosed and treated as early as possible after developing fever symptoms or showing other clinical characteristics or imaging features. With respect to high-risk cases, we must focus on any complications that arise and take effective measures to treat them immediately. This will significantly improve the prognosis of patients with severe infections.


Subject(s)
Antiviral Agents/administration & dosage , COVID-19 , Hospitalization/statistics & numerical data , Methylprednisolone/administration & dosage , Symptom Assessment , Adult , Anti-Inflammatory Agents/administration & dosage , COVID-19/epidemiology , COVID-19/physiopathology , COVID-19/therapy , COVID-19 Nucleic Acid Testing/methods , COVID-19 Nucleic Acid Testing/statistics & numerical data , China/epidemiology , Contact Tracing/methods , Contact Tracing/statistics & numerical data , Female , Humans , Lung/diagnostic imaging , Male , Outcome and Process Assessment, Health Care , SARS-CoV-2/isolation & purification , Severity of Illness Index , Symptom Assessment/methods , Symptom Assessment/statistics & numerical data , Time-to-Treatment , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed/statistics & numerical data
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